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Regenerative Medicine

When your body hurts, it affects your entire life. At PRIMed, our physicians don’t want to accept that you have to live life with pain. Whether from a soft tissue injury, cartilage damage or a more chronic condition, such as osteoarthritis, pain hurts.

You don’t have to give up what you love because of pain. PRIMed can help you REPAIR, RESTORE and REVITALIZE your joints and cartilage and get you going again.

We are pioneers in the use of regenerative medicine.

Who We Are

The Progressive Regenerative Institute of Medicine (PRIMed) was launched in July 2017 as a collaboration between Dr’s Kyle Young, Jason Lewis and their staff of highly trained experts at Commonwealth Pain & Spine.

The dual board certified physicians at PRIMed are dedicated to the rapid advancement of regenerative medicine therapies to treat many chronic pain conditions which include but are not limited to:

  • Knee Pain
  • Low Back Pain
  • Neck Pain
  • Major Joint Pain
  • Osteoarthritis
  • Sports Injury
  • Degenerative Joint Disease
  • Degenerative Disc Disease
  • Tendon Injury

Regenerative medicine seeks to cure injury, pain, and disease instead of simply treating and managing it. Even people who may have been considered incurable or untreatable in the past have the ability to flourish after undergoing regenerative medicine protocols.

Since the launch of the institute, significant advancements have been made in the treatment of these conditions and patients are reporting significant positive benefit. The PRIMed headquarters are centrally located in Louisville, Kentucky – easily accessible to much of the US population. The clinic features state-of-the-art fluoroscopy equipment, mild sedation provided by CRNA’s, centrifuge and filter technologies and may other value adds for patients. Dedicated patient care coordinators are available to patients to assist them in navigating the process from initial consult to treatment.

Jason Lewis, M.D.
Jason Lewis, M.D.

Dr. Lewis is certified by the American Board of Anesthesia in Anesthesia with a sub-specialty certification in Pain Medicine and holds a Kentucky and Indiana Medical License. Dr. Lewis earned his Doctor of Medicine degree from the University of Louisville in 2004 and has since completed a General Surgery Internship, Anesthesia Residency, and a Pain Medicine Fellowship. Dr. Lewis is a Diplomat of the Board of Anesthesia, and member of American Society of Anesthesia, Kentucky Society of Anesthesia, American Medical Association, Greater Louisville Medical Society, and Kentucky Medical Association. He has worked as a faculty member at University of Louisville’s Department of Anesthesia and as a Staff Physician/Pain Medicine Liaison at a major hospital. Dr. Lewis also has his private pilot’s license and is an FAA aviation medical examiner.

Kyle Young, M.D.
Kyle Young, M.D.

Dr. Young is Board Certified in the specialties of pain management and anesthesiology. He graduated magna cum laude from the University of Georgia with a B.S. in microbiology in 2001 and obtained his M.D. from the Medical College of Georgia in 2005. While completing his residency in Anesthesiology at the University of Louisville in Louisville, KY, he also served as Head of Medical Student Recruitment and was a member of the Resident Review Committee and Curriculum Committee. Dr. Young chose to continue his education and pursue a fellowship in pain management at the University of Louisville because of his desire to have an impact on his patients’ lives. The specialty of Interventional Pain Management affords Dr. Young the potential for long-term rewarding relationships with his patients. Dr. Young is licensed in both Kentucky and Indiana.

When your body hurts, it affects your entire life.

At PRIMed we can offer state of the art procedure suites, mild sedation, xray and ultrasound guided injections. We also employ cutting edge treatments in regenerative medicine such as Alpha 2 Macroglobulin (A2M) injections.

A2M is a preexisting molecule that can be found in your blood produced naturally by your liver to remove proteases associated with cartilage cell and tissue breakdown within the joint or disc space. An A2M injection contains a concentrated dose 6x more than what already occurs in your blood naturally. When this level of A2M is placed directly into your joint or disc space, it can provide the necessary amount of A2M to bind and remove destructive proteases associated with cartilage cell and tissue breakdown within the joint or disc space.

Another ground breaking treatment uses Human Amniotic Therapy. While 100% Pure Amniotic Fluid contains an impressive array of regenerative factors, there are no live stem cells, dead tissue, or debris in this product, as the FDA does not allow for stem cells to be present in any amniotic based product at this time. The product is intended to enable your body’s ability to repair itself by recruiting your own cells to do the work.

All 100% Pure Amniotic Fluid products are volunteered from pre-screened, healthy donors who have been thoroughly tested for disease, and obtained during full-term caesarian births – what an incredible gift with the blessing of life!

In addition, we also employ the use of your own body’s Bone Marrow Aspirated Stem Cells. These cells have been shown to have tremendous regenerative capabilities. Because of their high potency, physicians have used them in a wide variety of regenerative medicine treatment applications, including wound healing, cardiovascular grafts, soft tissue and cartilage repair, neurodegenerative diseases, post-mastectomy repair, and cosmetic applications.

Let us introduce you to how regenerative medicine can help you feel better.

What Is Regenerative Medicine

The National Institute of Health defines Regenerative Medicine as a rapidly developing field that has the potential to transform the treatment of human disease and injury through innovative new therapies that offer faster and more complete recovery. Moreover, Regenerative Medicine has significantly fewer side effects and risks of complication than surgery or drug therapies.

Modern medicine as we all know it today isn’t really very modern.

Though great progress has been made in medicine, current treatments are increasingly unable to keep pace with patients' needs, especially given our aging population. There are few effective ways to treat the root causes of many diseases and injuries. In many cases, clinicians can only manage patients' symptoms using medications, devices or surgery.

Case in Point: if you damage a major joint or suffer from osteoarthritis, your doctor will most commonly recommend the following age-old treatment algorithm:

First, they may prescribe rest, anti-inflammatories, analgesics and physical therapy. When those don’t achieve results and the pain persists, things progress pretty quickly from there. Traditional interventional treatments follow: Corticosteroid Injections and Viscosupplementation (Hyaluronic Acid injections). In the blink of an eye, you are staring down evasive surgeries and joint replacements as the "only option".

There are now other options

Pioneers in the advancement of regenerative medicine like PRIMed are changing the way physicians approach damaged or diseased joints. Instead of treating pain and injury with surgery, implants and drugs, regenerative medicine attempts to harnesses your body’s own ability to heal and boosts it in a very powerful and effective way.

Regenerative medicine itself isn't new — the first advancements were achieved decades ago and have been progressing in overseas markets for years. Regenerative medicine is most often considered a branch of "translational research in tissue engineering and molecular biology" which deals with the "process of replacing, engineering or regenerating human cells, tissues or organs to restore or establish normal function".

The term "regenerative medicine" was first used in a 1992 article on hospital administration by Leland Kaiser. Kaiser's paper closes with a series of short paragraphs on future technologies that will impact hospitals.

One paragraph had "Regenerative Medicine" as a bold print title and stated, "A new branch of medicine will develop that attempts to change the course of chronic disease and in many instances will regenerate tired and failing organ systems."

The widespread use of the term regenerative medicine is attributed to William A. Haseltine (founder of Human Genome Sciences). Haseltine was briefed on the project to isolate human embryonic stem cells and embryonic germ cells at Geron Corporation in collaboration with researchers at the University of Wisconsin-Madison and Johns Hopkins School of Medicine. He recognized that these cells' unique ability to differentiate into all the cell types of the human body had the potential to develop into a new kind of regenerative therapy. Explaining the new class of therapies, he used the term "regenerative medicine" in the way that it is used today: "an approach to therapy that employs human genes, proteins and cells to re-grow, restore or provide mechanical replacements for tissues that have been injured by trauma, damaged by disease or worn by time" and "offers the prospect of curing diseases that cannot be treated effectively today, including those related to aging.


When your body hurts, it affects your entire life.

Regenerative medicine holds the promise of definitive, affordable health care solutions that heal the body from within.

Many regenerative medicine therapies are available currently and others are being added as advancements progress.


Rejuvenation means boosting the body's natural ability to heal itself. If you have ever cut yourself, you are aware that your skin heals within a few days, but other joints and tissues don't repair themselves as readily. PRIMed physicians help cells in the body once thought to be no longer able to divide (considered terminally differentiated) to remodel and regain some ability to self-heal.


Regeneration involves delivering specific types of cells or cell products to diseased tissues or joint spaces, where they will ultimately restore tissue and function. This can be done through cell-based therapy or by using cell products, such as growth factors. Bone marrow aspirated stem cell therapies are an example.


Hear From Kevin R.

Curbside & Walk-in: Parking lot signage is very modern and polished like a premium medical brand. Seeing PRIMED at the door helped reinforce I was at the right location. That said, that was needed and provided the needed reinforced due me needing to confirm the location for my appointment. I was looking for that in or on the forms I was mailed to have completed for my visit.

Check in: I’ve been greeted with a positive attitude on both appointments, and have waited less than 5 minutes each time.

Office visits: Bobbi has been incredibly helpful as has all office staff. The culture feels very positive, appropriately empathetic, encouraging of the results to come with a dedication to resolving the underlying issue.

Procedure: The assistant was very professional. She was able to have me fully prepped in a way that felt very fluid once Doctor Lewis came in. The procedure was surprisingly quick, even though it was nearly exactly as Bobbi said it would be. The pain level was very low. Doctor Lewis came across as an expert. There’s no way I would have thought this was inside of his first ten or less procedures. His bedside manners were both personal and professional. The only thing I would change is a little more explanation of the procedure. This is probably person to me just because of wanting to know the details and science of procedures.

Results: Once the local anesthesia wore off I still felt a significant amount of relief. My knees did feel a little ‘full’, and still do just slightly as I’m sitting with knees bent while typing this. The amazing thing is how many time I commented last night that I couldn’t believe I did have knee pain getting up or sitting down like I normally do. This has resulted in increased energy and overall happiness. Even my sleep improved due to less knee pain. I’m looking forward to sharing more when I write next week. Again, I can’t thank you enough for your gift.

Kevin R.

Hear From Wesley H.

In October 2013, I had knee surgery and didn’t think it was really all that big an issue.  People had knee scopes all the time and had no problems after.  Little did I know, it was just the first sign of knee issues I would have for many years going forward.  It took me much longer than I ever anticipated to get back to the activity level I was comfortable with.  I have always been very active whether it be playing soccer or going to the gym 3-4 times a week.  But after my knee surgery, my knees began to progressively become more and more sore after any kind of activity and even got to the point that just standing for long periods was very uncomfortable and bordering on painful.  I began to have steroid injections in my knees about a year ago and they would help for a month or maybe two, but then I was right back where I started.  It had become so bad that I was having to wear support braces sometimes just to work and definitely when I went to the gym.  Even walking short distances to try and stay active left my knees throbbing for hours and days after.  I was starting to get concerned that I was going to have to have knee surgery again.  Then I was turned onto A2M regenerative injections and thought it was definitely worth a shot.  I really didn’t want to do surgery again.  I didn’t know what to expect.  I knew what steroids had done for me and was just hoping for something a little better that would make standing bearable and allow me to be my active self again.  It surpassed anything I could have expected. Day 1 after the injections, I had 100% relief from the soreness and aching I had been experiencing for months. Could this be a fluke? So I had to test it out.  I started by walking a mile and still, to my amazement, no pain.  So came the next test.  Time to go to the gym and do a hard legs work out.  Once again, the same result.  I had better range of motion then I had had in many months and for the first time in a while, I was able to do any exercise I wanted and still didn’t have any discomfort during or after my workout.  I couldn’t believe it.  So finally I had to push myself to the ultimate test.  Since my knee surgery, I hadn’t run on a concrete surface.  I had always stuck to a treadmill or elliptical.  So I decided to take it outside to the concrete.  I started off slow.  First day, I did a mile run around my neighborhood and it felt terrific.  No issues whatsoever.  So the next day, I went 2 miles and the next 3.  And still, the same result.  No discomfort.  It was like I was back in high school playing soccer again.  I am now about 2 months out from having my initial injections, and I still have a solid 75% pain relief with no let up in sight.  I am back in the gym working out as much as I want and when I am at work, I don’t have to find a chair to put close just in case I need to sit down. It has been without a doubt one of the best decisions I have made in a long time and I am excited to see just how long the relief continues!  I have no problem saying that I was a skeptic but my view has definitely changed.  I would recommend A2M to anyone that feels like they have exhausted all their options…because there is.

Wesley H., CRNA, APRN, MS, BSN

Hear From Dan M.

Over the past 10 years I have suffered from severe OA in both knees. The OA in my knees is a combination of years of wear and tear playing sports and bad genes considering OA runs on both sides of my family. I turn 50 next month and decided I wanted to do everything possible to hold off knee replacements for as long as possible. Over the past 10 years I have had both Knees scoped, multiple Synvisc injections, and PRP as well to help manage the OA pain. The Synvisc and PRP helped relieve pain a great deal the only problem is that the pain would return 3 to 4 months after the injections.

After exploring other options to help relieve the OA knee pain I decided that A2M injections may be the longer lasting OA relief I have been searching for that could potentially promote tissue growth in my aching knees. The pain before the A2M injections was daily an 8 or 9 on a 10 point scale. Walking my dogs or going up and down steps had turned into a every day struggle.

After consulting with Commonwealth Pain & Spine I knew that A2M injections made sense as the best option for me due to the excellent results that patients have experienced with pain relief with A2M injections in their practice. My entire experience with Commonwealth Pain & Spine was top notch. The entire staff took the time to explain the entire process of ATM injections and I never felt rushed. The thorough explanation of the A2M injections and treatment process was extremely helpful and interesting. The fact that they would be using my own blood to separate the good healthy plasma from the not so healthy plasma was reassuring and extremely interesting. The videos that explain step by step what to expect with A2M injections and the procedure provide a way to both be relaxed with the procedure and confident that the results should be long lasting. More than just a short term band aid like Synvisc or even PRP.

The day of the procedure couldn’t have been a easier or smoother experience. They took some vials of blood that took less than 5 minutes and was easier than if you donated blood at a blood drive. The next step was simply relaxing for about 30 minutes while the special machine spun my blood and separated the healthy plasma from the not so healthy plasma. The A2M procedure that Dr. Lewis performed surprised me in terms of how quick and painless it was. The nice part about the procedure is that Dr. Lewis gives you a injection for pain and then immediately follows up with the A2M injection directly into the joint. Dr. Lewis gave a series of 6 to 8 injections into each of my knees. The technology is really neat because you can actually see the screen that Dr. Lewis is looking at to insure that the A2M injections are pin point accurate into the compartments of my knee. The pain from the injection was similar to what I experienced having a Synvisc injection. Very little discomfort compared to the relief I had from the constant OA pain. The entire procedure took about 15 minutes and then I waited for about 30 minutes afterward before driving myself home.

Results after procedure:
The first couple of days after the procedure my knees felt kind of heavy. They appeared a little swollen as well which I was told would be the case and expected. After about 3 days the feeling of my knees seeming heavy went away along with the swelling. My pain went from a 8 or 9 before the procedure to no pain at all. Walking the dogs and walking up and down steps are no longer an issue. I have no pain at all in either of my knees. The reassuring aspect of A2M injections is the fact that the relief is complete in both knees and long lasting rather than a band aid for a few months.

Dan M.

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